Teddi and older sister Nala

Toddler is first UK patient to have revolutionary drug for fatal condition, but it's too late for her sister, 3, with same disorder
Maria Pearson has served 35 years in prison

UK's longest-serving female prisoner, who stabbed ex-husband's girlfriend to death in jealous attack, could finally be freed
Harold Shipman murdered more than 200 patients

Life insurance advert featuring joke about mass murdering doctor Harold Shipman banned

Ahead of the meeting, Nato secretary-general Jens Stoltenberg said defence ministers would work to strengthen the alliance's deterrence and defence

West risks running out of ammunition as Putin prepares for 'more war', warns NATO chief

The searching for missing mum Nicola Bulley continues

'Stained' glove found in hunt for missing Nicola Bulley yards from where she vanished

Drug dealer who mocked police is jailed for two years

Drug dealer who taunted police on Facebook while on the run is jailed for two years

Candlelit vigils are being held for Brianna Grey, who was found stabbed to death in a park on Saturday, with further events in tribute to teenager planned across the country.

Candlelit vigils held for trans teenager Brianna Ghey following fatal park stabbing

A British national has died in Ukraine, the Foreign Office has confirmed, becoming the eighth to be killed in the war-ravaged country.

British national dies in Ukraine, Foreign Office confirms

Students of Manchester Metropolitan University, Jack Spencer Furmston and Ben Camphor were walking home in Manchester when they saw dog owner, Batu Akyol, struggling to handle his dog lead.

Round of ap-paws: Students unite to rescue dog that fell in Manchester canal

A first convoy of UN aid entered northwest Syria from Turkey via the newly-opened Bab al-Salam crossing on Tuesday, according to spokespeople for the world body.

First UN aid trucks enter quake-hit northwest Syria from Turkey via newly-opened crossing

Pistorius, 36, widely known as 'Blade Runner' due to his blade-like carbon fibre prosthetics, was convicted of culpable homicide in 2015 for the murder of then-girlfriend Steenkamp.

Oscar Pistorius to get 24-hour police protection upon release, as Steenkamp's father calls latest meeting 'traumatising'

Lilt has been removed from UK supermarket shelves and will be rebranded as Fanta Pineapple and Grapefruit from 14 February, said the brand's owner, Coca-Cola.

Lilt axed after almost 50 years on UK shelves as drink is rebranded

The group is facing punishment for a spate of robberies

'Rolex rippers' caught after bungling watch robbers leave phone in car and pose with stolen timepieces

Officers investigating the fatal stabbing of Brianna Ghey, 16, (left) have been given more time to question two teenage suspects arrested on suspicion of her murder.

Officers investigating fatal stabbing of teenager Brianna Ghey given extra time to question suspects

Camilla will wear Queen Mary's crown at King Charles' coronation "in the interests of sustainability and efficiency".

Camilla to wear Queen Mary's crown at King Charles' coronation

A speedboat skipper who crashed into a buoy leaving Emily Lewis (L) fatally injured has been cleared of manslaughter.

Speedboat skipper cleared of manslaughter after buoy crash that killed teenager

An inquiry into how Couzens' crimes were investigated was launched

Officers face misconduct hearings over alleged failures during investigation of Wayne Couzens' crimes

The luxury resort played host to 100 Energy Warehouse 'partners' following promising sales figures

Outrage as energy firm sends 100 people on luxury £600-a-night Maldives getaway as millions struggle with energy bills