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David Cameron has opened up about the death of his son Ivan from a rare condition

David Cameron opens up on the death of his son aged 6 as he leads push for treatments for rare diseases

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Car insurance is more expensive in more deprived parts of the UK

Car insurance costs hundreds of pounds more for drivers living in deprived areas

Bank of England in the City of London (stock image)

Inflation falls to 1.7% the lowest rate in three years ahead of first Labour Budget

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David Cameron speaks to LBC

David Cameron calls for UK to sanction two Israeli ministers as change on arms embargo 'didn't satisfy anybody'

Jay Slater's mum has responded to the claims

'Say or stay out of it': Jay Slater's mum hits out at TV detective after he claimed to know real reason he left Airbnb

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Esther Rantzen said Kim Leadbeater was 'extraordinary'

Esther Rantzen hails Labour's 'extraordinary' Kim Leadbeater for introducing assisted dying bill

General Sir Michael Jackson has died aged 80

Former British army chief General Sir Mike Jackson dies aged 80, as tributes paid to 'great leader of men'

Rachel Reeves is said to be preparing £40 billion of spending cuts and tax rises

Labour 'prepare £40 billion in tax rises and spending cuts', as Chancellor admits to facing 'difficult decisions'

Sara Sharif was found at home by police

Chilling footage shows police entering Sara Sharif's home to find dead girl after father 'said he killed her'

Prince William throws an American football as he attends a NFL Foundation NFL Flag event on Tuesday

Prince William tries American football - and gains plaudits for 'unbelievable arm'

Thomas Tuchel will be the next England manager

Thomas Tuchel agrees to become new England manager after former Chelsea boss approached by FA

Israeli airstrikes in Gaza

US gives Israel 30-day deadline to improve Gaza's humanitarian situation or risk military aid

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Robert Jenrick

Robert Jenrick says 'tough love' needed to get people back to work, with over 9 million without a job

Muhammad Choudhary, 41, from east London, was sentenced to seven years in prison at the Old Bailey

Man jailed for terror offences after sending weapon parts abroad for Taliban fighters

Taxi driver Urfan Sharif, 42, is on trial at the Old Bailey accused of his daughter's murder alongside Sara's stepmother, Beinash Batool, 30, and uncle, Faisal Malik, 29

Sara Sharif's dad accused of writing 'I lost it and killed my daughter' on chilling note left by ten-year-old's body

Border Force officer holds a placard at a picket line outside Heathrow Airport, during strikes over changes to their working conditions, in London, on April 29, 2024.

Government cleaners vote to strike over pay and working conditions

Her mentor Nicola Lightfoot said Letby did not have the 'overall characteristics' to become a successful registered nurse

Lucy Letby initially failed final year placement as student nurse after mentor found her 'cold', inquiry hears

Russian emergency workers pull Mikhail Pichugin ashore after he was rescued by a fishing vessel following 67 days adrift in the Sea of Okhotsk

Castaway rescued after ten weeks stranded at sea but relatives 'found dead in boat'