First patient gets Pfizer's anti-Covid pill designed to stop coronavirus replicating

1 September 2021, 17:06

The pharmaceutical company has begun patient trials.
The pharmaceutical company has begun patient trials. Picture: Alamy

By Emma Soteriou

The first patient has been given a dose of an anti-viral pill in a clinical trial by Pfizer - designed to stop coronavirus replicating once people start showing symptoms.

The drug, which has entered mid-to-late-stage trials, is intended to be taken when individuals first start to show symptoms of Covid-19.

Around 1,140 participants have been enrolled in the randomised, double-blind patient trials. Those involved will receive either the pill or placebo every 12 hours for five days.

The pill is designed to block the activity of a key enzyme that is needed for coronavirus to replicate.

It comes as Pfizer has been up against the US-based Merck & Co Inc and the Swiss Roche Holding AG to develop the first anti-viral pill against the disease.

To date, Gilead Sciences Inc's remdesivir, administered intravenously, is the only approved antiviral treatment for Covid-19 in the United States.

Read more: Mu: New Covid strain designated variant of interest by WHO

Read more: Teenage Covid victim branded 'Satan' by anti-vaxxers for telling youngsters to get jab

Pfizer-BioNTech Covid-19 vaccine approved for use in 12 to 15-year-olds

The study is part of "a global clinical development programme, consisting of multiple ongoing and planned clinical trials" to evaluate the potential use in a broad population of patients, the pharmaceutical company said.

If the trial proves successful, Pfizer suggested in July that it would file for potential emergency use authorisation further down the line.

The company's chairman, Albert Bourla, tweeted that he was "pleased" to share that trials had moved forward for the pill specifically designed to combat Covid in non-hospitalised, low-risk adults.

Trials for those at an increased risk of progressing to severe illness if they caught Covid began in July.

Meanwhile, Pfizer's clinical trials for the pill first began in March 2021.

More than 90 million Brits have been vaccinated against the virus so far, with booster jabs also expected in coming months for those most vulnerable.

More Latest News

See more More Latest News

Matt Gaetz withdraws as Donald Trump's nominee for attorney general amid sexual misconduct allegations

Donald Trump nominates Pam Bondi for attorney general hours after Matt Gaetz withdraws

Starmer has backed the International Criminal Court over its arrest warrant for Netanyahu

Netanyahu faces arrest if he travels to Britain as Starmer vows to enforce International Criminal Court warrant

Yvette Cooper has branded the Rwanda scheme a "complete con."

Yvette Cooper to crack down on anti-social behaviour with new 'respect orders' as repeat offenders face jail time

King Charles III And Queen Camilla on Coronation Day

King Charles' coronation cost taxpayer £72 million, report reveals

Pep Guardiola, Manager of Manchester City

Pep Guardiola signs two-year contract extension with Manchester City

Captain Tom's Daughter Hannah Ingram-Moore

Behaviour at Captain Tom charity left ex-boss 'gobsmacked'

Armed robbers attempted to break into the star's Sunderland home.

Masked machete-wielding robbers break into Charlotte Crosby's home while she is upstairs with two-year-old daughter

Police have released new CCTV of Harshita Brella and her husband

Chilling CCTV released of Harshita Brella and prime murder suspect husband on night she was killed

First photos of Gavin and Stacey Christmas Special as James Corden and Ruth Jones mark triumphant finale

First photos of Gavin and Stacey Christmas Special as James Corden and Ruth Jones mark show's triumphant finale

King Charles performs a Hongi, a traditional Maori greeting, with Mere Takoko

King Charles shares traditional Maori nose rub greeting with activist as he launches environmental charity

Putin issued a chilling threat to the West as he confirmed Russia launched a ballistic missile against Ukraine

Putin issues chilling warning to UK and US as he confirms Russia hit Ukraine with new 'experimental' ballistic missile

Telegraph writer Allison Pearson.

Police drop investigation into journalist Allison Pearson over tweet - as review to be launched over handling of case

Exclusive
Angela Rayner has paid tribute to John Prescott

Angela Rayner says John Prescott 'used to call her after PMQs to remind her to stay true to who she is'

Four men have been arrested accused of attempting to rob a mobile phone store

Undercover police arrest four men after EE shop raided by masked gang

Matt Gaetz withdraws as Donald Trump's nominee for attorney general amid sexual misconduct allegations

Matt Gaetz withdraws as Donald Trump's nominee for attorney general amid sexual misconduct allegations

Donald Trump Watches SpaceX Launch Its Sixth Test Flight Of Starship Spacecraft

Elon Musk pledges to fire civil servants who work from home